A recent study investigated the effects of psilocybin, the active ingredient in magic mushrooms, in mice and demonstrated its long lasting effects on the growth and structure of dendritic spines. The authors suggest these changes may underlie the putative rapid and sustained antidepressant effects of psychedelic drugs. In this video, I will give a brief overview of these very interesting results!
I’d be happy to hear your thoughts about this study and continue the discussion down below in the comments section.
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Also check out my video on Psilocybin and 5HT2A receptors:
Psilocybin induces rapid and persistent growth of dendritic spines in frontal cortex in vivo
Ling-Xiao Shao, Clara Liao, Ian Gregg, Pasha A Davoudian, Neil K Savalia, Kristina Delagarza, Alex C Kwan
PMID: 34228959 DOI: 10.1016/j.neuron.2021.06.008